Significance of bacterial virulence and immune defence
نویسنده
چکیده
The first encounter of the neonate with Esch. coli consists of the normal intestinal colonization. Already at this stage the body is able to cope with these micro-organisms, accepting them as a part of the normal intestinal flora, but hindering them from invading the tissues. It is obvious, however, that from this early colonization onward the infant and then the child is carrying a reservoir of potentially pathogenic micro-organisms which are separated from the tissues only by the mucous membranes, supported by the host defence. This paper discusses Esch. coli infections in childhood with special reference to bacterial virulence factors and the immune defence mechanisms involved.
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